Mass Spectrometer
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 ETP Model AF511 Electron Multiplier MPN 14511 for 5970MSD Mass Spectrometer $500.00 Time Remaining: 29d 8h 54m Buy It Now for only: $500.00 |
 FINNIGAN MAT GCQ MASS SPECTROMETER $500.00 Time Remaining: 2d 12h 50m |
 FINNIGAN MART GCQ GAS CHROMATOGRAPH GC MASS SPECTROMETER W PROBE $600.00 Time Remaining: 24d 10h 3m Buy It Now for only: $600.00 |
 MKS Model HAL 2 301 Quadrupole Mass Spectrometer $99.99 Time Remaining: 4d 23h 59m Buy It Now for only: $99.99 |
 Thermo Ion Max Source Housing APCI Chemical Ionization Probe Mass Spectrometer $4,450.00 Time Remaining: 29d 5h 48m Buy It Now for only: $4,450.00 |
 Thermo Finnigan Bioanalysis DYNAMO TOF Mass Spec Spectrometer $3,995.00 Time Remaining: 21d 11h 56m Buy It Now for only: $3,995.00 |
 FINNIGAN GCQ GCMS GAS CHROMATOGRAPH MASS SPECTROMETER GC MS ION PAIR SOFTWARE $5,950.00 Time Remaining: 25d 31m Buy It Now for only: $5,950.00 |
 Thermo Finnigan Surveyor MSQ Mass Spectrometer System with Autosampler $5,999.99 Time Remaining: 3d 2h 7m Buy It Now for only: $5,999.99 |
 THERMO FINNIGAN QUEST SCIENTIFIC TRACE GC GAS CHROMATOGRAPH MS MASS SPECTROMETER $9,999.98 Time Remaining: 8d 9h 56m Buy It Now for only: $9,999.98 |
 Quarapole RF Mass Spectrometer Varian Conflat Vacuum Diffusion MKS $800.00 Time Remaining: 5d 8h 1m Buy It Now for only: $800.00 |
 Waters Micromass ZMD Mass Spectrometer $599.00 Time Remaining: 9d 3h 39m Buy It Now for only: $599.00 |
 FISONS MD 800 MD800 Mass Spectrometer For GC MS Gas Chromatograph System $2,750.00 Time Remaining: 26d 23h 33m Buy It Now for only: $2,750.00 |
 Waters Micromass Quattro II Triple Quadrupole Mass Spectrometer $4,500.00 Time Remaining: 23d 4h 53m Buy It Now for only: $4,500.00 |
 Waters Micromass Quattro II Triple Quad mass Spectrometer $8,000.00 Time Remaining: 2d 3h 55m Buy It Now for only: $10,000.00 |
 BALZERS QMG 064 MASS SPECTROMETER RGA $149.99 Time Remaining: 15d 31m Buy It Now for only: $149.99 |
 Agilent 5973N MSD with 6890 GC and Diffusion Pump Mass Spectrometer $39,000.00 Time Remaining: 23d 3h 56m Buy It Now for only: $39,000.00 |
 Mass Spectrometer Waters Micromass Q TOF Micro Sys $74,250.00 Time Remaining: 28d 3h 34m Buy It Now for only: $74,250.00 |
 FINNIGAN LCQ Mass Spectrometer System w computer mause monitor manuals 4331 $17,999.00 Time Remaining: 2d 4h 21m Buy It Now for only: $17,999.00 |
 MICROMASS PLATFORM LC LIQUID CHROMATOGRAPHY MASS SPECTROMETER NO SOFTWARE USE $3,250.00 Time Remaining: 5d 9h Buy It Now for only: $3,250.00 |
 Thermo Finnigan TSQ Quantum Mass Spectrometer $52,000.00 Time Remaining: 23d 2h 47m Buy It Now for only: $52,000.00 |
 Mass Spectrometer Hewlett Packard GCMS $30,892.95 Time Remaining: 28d 3h 35m Buy It Now for only: $30,892.95 |
 MDS Sciex Qstar Mass Spectrometer RF Coil $199.00 Time Remaining: 26d 22h 10m Buy It Now for only: $199.00 |
 Waters Micromass ZQ EMD 1000 Mass Spectrometer Head Probe Adjuster M946843CC1 $1,659.17 Time Remaining: 9d 4h 30m Buy It Now for only: $1,659.17 |
 WATERS MA3889 Micromass LockSpray p n 3889001DC2 100 240VAC f Mass Spectrometer $249.99 Time Remaining: 13d 4h 59m Buy It Now for only: $249.99 |
 Waters Micromass LCT TOF Mass Spectrometer $5,325.00 Time Remaining: 29d 12h 52m Buy It Now for only: $5,325.00 |
 Fisons VG Quattro Quadrupole Mass Spectrometer $1,999.99 Time Remaining: 6d 12h 5m Buy It Now for only: $1,999.99 |
 Micromass Maldi R Mass Spectrometer $750.00 Time Remaining: 6d 22h 9m Buy It Now for only: $1,500.00 |
 Thermo Finnigan TSQ7000 Mass Spectrometer Quadrupole Assemblies Collision Cell $2,899.99 Time Remaining: 20d 12h 18m Buy It Now for only: $2,899.99 |
 4 NEW Veeco Tungsten GA 4 Filaments for Mass Spectrometer Tube MSF 140 $49.95 Time Remaining: 16d 9h 13m Buy It Now for only: $49.95 |
 Hewlett Packard 5989A Mass Spectrometer GC $4,231.50 Time Remaining: 4d 22h 5m Buy It Now for only: $4,231.50 |
 Agilent G2445A 1100 LCMS LC MSD Trap Mass Spectrometer $29,000.00 Time Remaining: 14d 4h 21m Buy It Now for only: $29,000.00 |
 MDS Sciex Qstar Mass Spectrometer XY X Y Positioning Stage $129.00 Time Remaining: 8d 23h 25m Buy It Now for only: $129.00 |
 FINNIGAN MAT LCQ MASS SPECTROMETER SYSTEM $6,000.00 Time Remaining: 13d 55m Buy It Now for only: $6,000.00 |
 Balzers QMG 112A Quadrupole Mass Spectrometer $499.95 Time Remaining: 12d 9h 11m Buy It Now for only: $499.95 |
 Agilent 5975 inert GC MS System Mass Spectrometer $52,000.00 Time Remaining: 23d 3h 12m Buy It Now for only: $52,000.00 |
 Mass Spectrometer Waters LCT System $24,750.00 Time Remaining: 28d 3h 35m Buy It Now for only: $24,750.00 |
 MASS SPECTROMETER UNIT SPECTROSCOPY SPEC PERKIN LAMBDA $3,500.00 Time Remaining: 22d 4h 53m Buy It Now for only: $3,500.00 |
 Perkin Elmer SCIEX prOTOF 2000 MALDI OTOF Proteomics Mass Spectrometer $84,000.00 Time Remaining: 11d 3h 15m Buy It Now for only: $84,000.00 |
 Thermo Finnigan LCQ DECA Electrospray Mass Spectrometer $26,500.00 Time Remaining: 6d 22h 9m Buy It Now for only: $29,500.00 |
 Mass Spectrometer Applied Biosystems LC MS MS $24,750.00 Time Remaining: 28d 3h 35m Buy It Now for only: $24,750.00 |
 Waters Micromass MLDI LR Mass Spectrometer $59,995.00 Time Remaining: 27d 2h 8m Buy It Now for only: $59,995.00 |
 mass spectrometer $30,000.00 Time Remaining: 27d 10h 8m Buy It Now for only: $30,000.00 |
 Ciphergen Bio Rad PBS II ProteinChip SELDI TOF MS Biology Mass Spectrometer $3,999.99 Time Remaining: 23d 21h 24m Buy It Now for only: $3,999.99 |
 Waters Mass Spectrometer Control Panel with Rheodyne 7010 Valve 5701 Actuator $499.99 Time Remaining: 24d 8h 3m Buy It Now for only: $499.99 |
 Mass Spectrometer Applied Biosystems Voyager DE PRO TOF MALDI $19,305.00 Time Remaining: 21d 6h 17m Buy It Now for only: $19,305.00 |
 Qstar Mass Spectrometer Component $1,116.00 Time Remaining: 9d 23h 40m Buy It Now for only: $1,116.00 |
 MDS Sciex Qstar Mass Spectrometer RF Coil $199.00 Time Remaining: 26d 22h 33m Buy It Now for only: $199.00 |
 MKS Mass Spectrometer Filament Head LM506 10366 1F1 Used $1,010.11 Time Remaining: 10d 2h 23m Buy It Now for only: $1,010.11 |
 Finnigan Mat Mass Spectrometer Controller SCAN 8 for Entech 7200 System $499.00 Time Remaining: 18d 2h Buy It Now for only: $499.00 |
 Varian Saturn 2000 GC MS system Mass Spectrometer $17,900.00 Time Remaining: 10d 23h 52m Buy It Now for only: $17,900.00 |
 Finnigan Newstar T70 Mass Spectrometer FT MS $7,500.00 Time Remaining: 2d 21h 50m Buy It Now for only: $7,500.00 |
 Thermo Finnigan LCQ DUO ESI Electrospray Mass Spectrometer $24,500.00 Time Remaining: 6d 22h 9m Buy It Now for only: $27,500.00 |
 PE Sciex API Qstar Mass Spectrometer Modules and Power Supply $2,325.00 Time Remaining: 29d 3h 26m Buy It Now for only: $2,325.00 |
 Agilent 1100 LC MSD Trap SL version Mass Spectrometer $32,000.00 Time Remaining: 23d 3h 9m Buy It Now for only: $32,000.00 |
 Agilent HP Mass Spectrometer Sensor Head HA3 5971 New $1,010.11 Time Remaining: 7d 1h 25m Buy It Now for only: $1,010.11 |
 Agilent 1100 G2445A LCMS Mass Spectrometer MSD LCMSD $20,250.00 Time Remaining: 22d 6h 57m Buy It Now for only: $20,250.00 |
 BIO RAD CIPHERGEN PROTEINCHIP PBS II MASS SPECTROMETER VARIAN TURBO V250 PUMP $4,100.00 Time Remaining: 6h 29m Buy It Now for only: $4,100.00 |
 Mass Spectrometer Applied Biosystems API 3000 LC MS MS $39,599.01 Time Remaining: 16d 8h 29m Buy It Now for only: $39,599.01 |
 Waters Xevo TQ Mass Spectrometer $165,000.00 Time Remaining: 24d 4h 17m Buy It Now for only: $165,000.00 |
 Ametek LC100 Dycor LC200S RGA Gas Analyzer Mass Spectrometer $499.00 Time Remaining: 15d 6h 50m Buy It Now for only: $499.00 |
 Reconditioned Turbo pump for Mass Spectrometer $2,500.00 Time Remaining: 17d 3h 4m Buy It Now for only: $2,500.00 |
 Thermo Finnigan AQA Liquid Chromatography Mass Spectrometer 220 24VAC Very Clean $2,500.00 Time Remaining: 20d 1h 52m Buy It Now for only: $2,500.00 |
 Perkin Elmer ELAN 6000 inductively coupled plasma mass spectrometer Refurbished $49,999.00 Time Remaining: 9d 5h 43m Buy It Now for only: $49,999.00 |
 Thermo Finnigan GCQ Gas Chromatograph Mass Spectrometer $1,499.00 Time Remaining: 6d 9h 49m Buy It Now for only: $1,999.00 |
 Ametek LC100 RGA Residual Gas Analyzer Mass Spectrometer RF Box Probe Head Cable $499.00 Time Remaining: 15d 6h 52m Buy It Now for only: $499.00 |
 M Bar Gauge from Mass Spectrometer $46.50 Time Remaining: 10d 1h 43m Buy It Now for only: $46.50 |
 Finnigan Mat Mass Spectrometer Varian GC Vac Pump $12,865.00 Time Remaining: 22h 28m Buy It Now for only: $12,865.00 |
 Agilent Varin ICP Mass spectrometer Varianinc ICP MS Varian V 301 V 700HT $10,000.00 Time Remaining: 24d 15h 42m Buy It Now for only: $10,000.00 |
 4 Waters LCT Mass Spectrometer Kilovolt Power Supplies $799.99 Time Remaining: 20d 4h 16m Buy It Now for only: $799.99 |
 MDS Sciex Qstar Mass Spectrometer Probe $549.00 Time Remaining: 29d 23h 32m Buy It Now for only: $549.00 |
 Extranuclear Mass Spectrometer Measurement System $1,875.00 Time Remaining: 38m Buy It Now for only: $1,875.00 |
 Waters LCT TOF Mass Spectrometer Cell Reflectron Parts $999.99 Time Remaining: 20d 3h 32m Buy It Now for only: $999.99 |
 TruLogic Mass Spectrometer Black Aluminum Housing $69.75 Time Remaining: 29d 23h 54m Buy It Now for only: $69.75 |
 PE Sciex Qstar Mass Spectrometer Component Harvard Apparatus 980921 $149.00 Time Remaining: 5d 1h 29m Buy It Now for only: $149.00 |
 API Qstar Mass Spectrometer Machined Hinge $64.17 Time Remaining: 24d 15m Buy It Now for only: $64.17 |
 TrueLogic Mass Spectrometer Components $139.50 Time Remaining: 23d 23h 58m Buy It Now for only: $139.50 |
 JEOL JMS T100LC AccuTOF Mass Spectrometer $30,000.00 Time Remaining: 1h 58m |
 MDS Sciex Qstar Mass Spectrometer Video Monitoring System $329.00 Time Remaining: 23d 23h 16m Buy It Now for only: $329.00 |
 API Heated Nebulizer for API3000 or API4000 Mass Spectrometer 5151 $1,999.00 Time Remaining: 1d 1h 14m Buy It Now for only: $1,999.00 |
 ANALYTICA IRIS HEXAPOLE ION GUIDE P N 104851 FOR MASS SPECTROMETER $325.00 Time Remaining: 6d 1h 14m Buy It Now for only: $325.00 |
 Finnigan Instruments 400 Quadrupole Mass Spectrometer $1,274.99 Time Remaining: 22d 2h 46m Buy It Now for only: $1,274.99 |
 MDS Sciex Qstar Mass Spectrometer PCB Interconnect 1002744 B $325.00 Time Remaining: 9d 21h 35m Buy It Now for only: $325.00 |
 Micromass Platform LZC Mass Spectrometer $18,000.00 Time Remaining: 9d 2h 17m Buy It Now for only: $18,000.00 |
 TrueLogic Mass Spectrometer Components $139.50 Time Remaining: 24d 2h 25m Buy It Now for only: $139.50 |
 Finnigan DPC Lab Direct Probe Controller+GCQ Gas Chromatograph+Mass Spectrometer $5,999.99 Time Remaining: 14h 5m Buy It Now for only: $5,999.99 |
 Qstar Mass Spectrometer Components RF Feedback 021221 A $744.00 Time Remaining: 11d 1h 24m Buy It Now for only: $744.00 |
 CEC Mass Spectrometer Electro Magnet Parts ++ $7,999.99 Time Remaining: 16d 23h 4m Buy It Now for only: $7,999.99 |
 Alpha Wire Shielded Mass Spectrometer Cable Wire $69.75 Time Remaining: 10d 2h 44m Buy It Now for only: $69.75 |
 Waters Micromass ZQ Mass Spectrometer $20,000.00 Time Remaining: 3h 5m |
 Qstar Mass Spectrometer Component 026093 A EMP $837.00 Time Remaining: 9d 23h 13m Buy It Now for only: $837.00 |
 API Qstar Mass Spectrometer MDS Sciex Motherboard 025171 $371.07 Time Remaining: 24d 38m Buy It Now for only: $371.07 |
 Finnigan Mat Inca 50 mass spectrometer $1,599.00 Time Remaining: 1d 5h 37m Buy It Now for only: $1,599.00 |
 Qstar Mass Spectrometer Component $69.75 Time Remaining: 18d 23h 31m Buy It Now for only: $69.75 |
 Fisons Mass Spectrometer Injector 7125 $162.75 Time Remaining: 10d 2h 11m Buy It Now for only: $162.75 |
 Qstar Mass Spectrometer Component 022765 B CFN 0094 $1,395.00 Time Remaining: 9d 22h 25m Buy It Now for only: $1,395.00 |
 Qstar Mass Spectrometer Component $1,395.00 Time Remaining: 9d 22h 8m Buy It Now for only: $1,395.00 |
 MDS Sciex Qstar Mass Spectrometer Component 018534 D $149.00 Time Remaining: 8d 23h 15m Buy It Now for only: $149.00 |
 ThermoQuest Finnigan LCQ Deca Mass Spectrometer and Dionex HPLC System $30,000.00 Time Remaining: 19d 1h 28m Buy It Now for only: $30,000.00 |
 Qstar Mass Spectrometer Component MDS Sciex $1,116.00 Time Remaining: 10d 2h 22m Buy It Now for only: $1,116.00 |
 Fisons Mass Spectrometer Component $69.75 Time Remaining: 11d 22h 58m Buy It Now for only: $69.75 |
Mass Spectrometer
Protein identification with Protein Pilot™ Software
Protein identification techniques which are essentially peptide identification/correlation techniques, have improved significantly over time. Edman degradation, the preferred technique for many years was simple and very powerful but it was very slow, since it identified one protein at a time. To identify one protein ID in a 60 min gradient would take about seven hours. Compare that to identification done using mass spectrometry routines; it can identify 10 – 50 Proteins in 30 minutes.
Some of the popular mass spectrometry protein identification techniques are peptide mass fingerprinting, sequence tag identification and ms/ms peptide identification. In ms/ms peptide identification a peptide is broken up using a mass spectrometer and the fragment ion masses are then used to search a sequence database.
There is intense competition among companies that operate in the mass spectrometry space to be the best at protein identification but with a vastly simplified user interface and the power to search for hundreds of modifications simultaneously, the Protein Pilot™ Software, developed by Absciex sets a new standard for quality and quantity of results in protein identification and biomarker discovery. The system is powerful, easy to use and provides tools to help you search, identify, and analyze hundreds of proteins and quickly find the information you need. Key features of Protein Pilot™ Software are:-
1. Tag-based probabilistic approach:
Search for hundreds of modifications and variants without an explosion of false positives using the innovative Paragon™ algorithm.
2. Robust protein reporting:
Determine and report the number of proteins and isoforms actually detected, including ambiguity among multiple accessions with the industry leading Pro Group™ Algorithm.
3. Integrated, rigorous false discovery rate (FDR) analysis:
Analyze the specificity and quality of your results at the highest level with decoy database searching.
Targeted, hypothesis driven protein/peptide quantitation using MRM (Multiple Reaction Monitoring) enables you to detect and measure hundreds of proteins in a given experiment at high sensitivity.
Protein Pilot™ Software has changed the protein identification and peptide quantitation paradigm. One doesn't have to specify details like mass tolerances, individual modifications, expected fragment ion types, or exceptions to cleavage rules. Simply enter the sample information you know, and the algorithm automatically optimizes the settings.
The Protein Pilot™ Software user interface is very easy to view and navigate through protein identification and quantitation results. The Protein ID view displays the proteins detected and the protein-peptide associations for each protein group, including the raw MS/MS spectrum and matching peaks. The Protein Quant view displays each measured protein ratio color-coded by P-value, so one can quickly see changes in expression levels.
Protein Pilot™ Software includes an automatic false discovery rate (FDR) analysis that gives you a rigorous defense of the quality of your results, using both conventional FDR analysis as well as novel extensions. If your typical workflow is gel-based analysis, you can submit PMF and PMF-combined searches on TOF/TOF data to Mascot for identification of gel spots.
It has ultimate flexibility and control as you can search data from any instrument. Protein Pilot™ FDR analysis supports instruments from several manufacturers. An open parameter control function allows you to add support for instruments not already included. A translation file is also available for accessing parameters such as new modifications, instrument settings, and digests agents.
Additional details & trial software downloads are available at www.absciex.com.
About the Author
Ryan Harris is a prolific writer for issues pertaining to the life science industry and has authored many research papers specifically on proteomics. His in-depth knowledge pertaining to mass spectrometry solutions is respected across the industry.
How does a mass spectrometer work? ?
I know a mass spectrometer is the most accurate way to determine the mass of an element...But how does it work?
How a mass spectrometer works
The basic principle
If something is moving and you subject it to a sideways force, instead of moving in a straight line, it will move in a curve - deflected out of its original path by the sideways force.
Suppose you had a cannonball travelling past you and you wanted to deflect it as it went by you. All you've got is a jet of water from a hose-pipe that you can squirt at it. Frankly, its not going to make a lot of difference! Because the cannonball is so heavy, it will hardly be deflected at all from its original course.
But suppose instead, you tried to deflect a table tennis ball travelling at the same speed as the cannonball using the same jet of water. Because this ball is so light, you will get a huge deflection.
The amount of deflection you will get for a given sideways force depends on the mass of the ball. If you knew the speed of the ball and the size of the force, you could calculate the mass of the ball if you knew what sort of curved path it was deflected through. The less the deflection, the heavier the ball.
Next time, you google your question.
The Mass Spectrometer